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Biogenics Research Institute
Other Respiratory Tract Disorders
Hypersensitivity Pneumonitis
Idiopathic Intersitial Lung Disease

Symptomatic Clinical Presentation
Although contaminations are very common, symptoms caused by these factors are much less than might be expected. There are many factors and circumstances that determine who would be affected including density of the contamination, duration of exposure, pre-existing conditions, and, perhaps most importantly, a genetic predisposition to respond to certain organic antigens.


Clinical presentations resulting from a contamination can be categorized based upon mechanisms and intensity of symptoms:

No clinical symptoms 80%
Nuisance symptoms 20%
Life-altering symptoms <0.01%
Life-threatening symptoms <0.03%

Pre-existing disorders aggravated by microbial contamination

Nuisance Symptoms

  • Allergic Rhinoconjunctivitis
  • Non-allergic Rhinoconjunctivitis

Life-altering Symptoms

  • Asthma, modest
  • COPD, with asthma
  • Other disorders with Reactive lower airways

Life-threatening Symptoms

  • Asthma, severe
  • COPD, with asthma
  • Severe Cystic Fibrosis

Disorders caused by microbial contamination

  • Nuisance Symptoms
  • Nasal congestion
  • Sneezing
  • Rhinorrhea
  • Blowing of mucous
  • Hacky cough
  • Ocular symptoms
  • Headache
  • Tiredness and fatigue
  • Shortness of breath
  • Throat clearing
  • Otic (ear) pressure
  • Post nasal discharge
  • Voice raspiness
  • Throat soreness
  • Dizziness
  • Lack of focus

Life-altering Symptoms

  • Severe cough
  • Severe asthma

Life-threatening Symptoms

  • Hypersensitivity Pneumonias
  • Infectious Pneumonias
  • Intractable Asthma